Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398702 | 1.00 | MEN1 (0.59) | MEN1KMT2AMAPTNFE2L2HPGD | |
| SCHEMBL11398705 | 1.00 | MEN1 (0.59) | MEN1KMT2AMAPTNFE2L2HPGD | |
| SCHEMBL5931364 | 0.77 | MEN1 (1.00) | MEN1KMT2AMAPTNFE2L2HPGD | |
| SCHEMBL10954720 | 0.76 | ALDH1A1 (0.40) | MAPTGAAALDH1A1BRD4CREBBP | |
| SCHEMBL9384993 | 0.76 | ALDH1A1 (0.40) | MAPTGAAALDH1A1BRD4CREBBP | |
| SCHEMBL10954717 | 0.76 | ALDH1A1 (0.40) | MAPTGAAALDH1A1BRD4CREBBP | |
| SCHEMBL13618094 | 0.69 | MEN1 (0.76) | MEN1KMT2AMAPTNFE2L2HPGD | |
| SCHEMBL10949094 | 0.66 | PAM (0.45) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL10949089 | 0.66 | PAM (0.45) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL28474124 | 0.65 | MEN1 (0.74) | MEN1KMT2AMAPTNFE2L2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56025154-A | — | — | None | — | — | JP | disclosed |
| JP-S5625154-A | AZETIDINONE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1981-03-10 | — | — | JP | disclosed |