SCHEMBL113990

SCHEMBL113990

Cc1cccc([SiH2]Cl)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.42
CYP2A6 P11509 3/20 0.38
CYP1A2 P05177 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
TSHR P16473 3/20 0.36
ACHE P22303 2/20 0.36
ALDH1A1 P00352 4/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.32
CD44 P16070 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707216 0.79
SCHEMBL29776862 0.77 TRPA1 (0.44) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL10696455 0.77 TRPA1 (0.44) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL2175294 0.75 TRPA1 (0.48) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL8967412 0.75 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL3200651 0.75 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL7768863 0.75 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL7179945 0.75 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL6857979 0.75 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2KEAP1
SCHEMBL704385 0.75 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 753 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119869608-A Preparation method of modified Ti-MSU molecular sieve catalyst, modified Ti-MSU molecular sieve catalyst and application 中国石油化工股份有限公司 2025-04-25 CN claimed
CN-119708496-A Preparation method of methyl phenyl vinyl MQ silicon resin 浙江恒业成新材料有限公司 2025-03-28 CN claimed
CN-118407275-A Novel porous calcium silicate and preparation process thereof 无锡成全投资发展有限公司 2024-07-30 CN claimed
CN-118122138-B Microporous membrane and preparation method and application thereof 湖南叶之能科技有限公司 2024-07-12 CN claimed
CN-118122138-A Microporous membrane and preparation method and application thereof 湖南叶之能科技有限公司 2024-06-04 CN claimed
CN-109678171-B Ti-MWW molecular sieve with high external surface area and high framework titanium content, and preparation method and catalytic application thereof 中国石油化工股份有限公司 2024-03-29 CN claimed
CN-111570216-B Composite protective film layer with silane transition layer, preparation method thereof and product 江苏菲沃泰纳米科技股份有限公司 2023-10-13 CN claimed
CN-115322368-B Linear polymer and preparation method and application thereof 北京航空航天大学 2023-08-08 CN claimed
CN-115873220-A Organic silicon modified imidazole curing agent and preparation method thereof 希立科高新材料科技(苏州)有限公司 2023-03-31 CN claimed
EP-3674438-B1 PREPARATION METHOD FOR HIGH INSULATION NANO-PROTECTIVE COATING HAVING MODULATION STRUCTURE JIANGSU FAVORED NANOTECHNOLOGY CO LTD (CN) 2023-03-29 EP claimed
WO-2004013103-A2 PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES THE PROCTER & GAMBLE COMPANY (US) 2004-02-12 WO claimed
EP-1343766-A1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES THE PROCTER & GAMBLE COMPANY (US) 2003-09-17 EP claimed
US-6525197-B1 Producing chemical intermediates for such as epothilone or epothilone analogues synthesis STUDIENGESELLSCHAFT KOHLE MBH (DE) 2003-02-25 US claimed
WO-2002048113-A1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES THE PROCTER & GAMBLE COMPANY (US) 2002-06-20 WO claimed
EP-1053215-B1 METHODS FOR PREPARING MACROCYCLIC PRODUCTS BY RING-CLOSING DIINE METATHESIS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-05-22 EP claimed
US-6365643-B1 Photoinitiators for cationic curing TH. GOLDSCHMIDT AG (DE) 2002-04-02 US claimed
EP-1117008-A2 UV-assisted chemical modification of photoresist images Axcelis Technologies, Inc. (US) 2001-07-18 EP claimed
US-5565540-A COHYDROLYZING TRIORGANOHALOSILANE AND DIORGANODIHALOSILANE IN PRESENCE OF BASIC COMPOUND IN TWO-LAYER LIQUID SYSTEM DOW CORNING TORAY SILICON CO., LTD. (JP) 1996-10-15 US claimed
WO-1996012723-A1 PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS FMC CORPORATION (US) 1996-05-02 WO claimed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US claimed