SCHEMBL2175294

SCHEMBL2175294

Cc1cccc([SiH2]O)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 5/20 0.42
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
TSHR P16473 2/20 0.36
ACHE P22303 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
MAPT P10636 3/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MEN1 O00255 1/20 0.32
AKR1B10 O60218 1/20 0.32
ABCB11 O95342 1/20 0.32
DHFR P00374 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6114402 0.79
SCHEMBL29776862 0.77 TRPA1 (0.44) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL27852210 0.77 TRPA1 (0.33) TRPA1ATMCYP1A2CYP2A6TSHR
SCHEMBL10696455 0.77 TRPA1 (0.44) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL7677167 0.76 TRPA1 (0.40) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL4435873 0.76 TRPA1 (0.40) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL113990 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL7768863 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL8967412 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL7179945 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529476-A Epoxy resin composition, preparation method and epoxy glass cloth laminated board 深圳市雄毅华绝缘材料有限公司 2025-02-28 CN claimed
CN-119431708-A In-situ inorganic hybridization reinforced polyurethane resin and preparation method thereof 丰源和泰(兰州)新材料有限公司 2025-02-14 CN claimed
CN-118813056-B High-foaming-rate liquid silicone rubber foam material and preparation method and application thereof 浙江申禾丽阳科技有限公司 2025-01-24 CN claimed
CN-116656211-B Water-based epoxy insulating paint and preparation method thereof 国网安徽省电力有限公司超高压分公司 2024-06-04 CN claimed
CN-117801316-A Composite polyether silicone oil emulsifier and preparation method and application thereof 万华化学集团股份有限公司 2024-04-02 CN claimed
CN-117705961-A Method for measuring hydroxyl content in low-viscosity hydroxyl silicone oil by utilizing soil sweeping and trapping principle 湖北兴瑞硅材料有限公司 2024-03-15 CN claimed
CN-117264183-A Bio-based polyester polyol and preparation method thereof 广东华博润材料科技有限公司 2023-12-22 CN claimed
CN-117004030-A Zirconium-silicon modified acrylic ester and preparation method thereof 广东工业大学 2023-11-07 CN claimed
CN-116656211-A Water-based epoxy insulating paint and preparation method thereof 国网安徽省电力有限公司超高压分公司 2023-08-29 CN claimed
CN-116515279-A High-temperature-resistant flame-retardant material for new energy high-voltage wire and preparation method thereof 东莞市通锦新材料科技有限公司 2023-08-01 CN claimed
CN-116376139-A Bi-component flame-retardant organosilicon crosslinked cable material and preparation method thereof 台州市开翼环保科技有限公司 2023-07-04 CN claimed
CN-114621368-A Ethylene gas-phase polymerization grade switching agent and preparation method thereof 中国石油天然气股份有限公司 2022-06-14 CN claimed
EP-0679674-B1 Method for preparing diorganopolysiloxane having a functional group at only one end of the molecular chain DOW CORNING TORAY SILICONE (JP) 2000-09-20 EP claimed
US-5486635-A WEATHER AND WATER RESISTANCE DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-01-23 US claimed
EP-0679674-A2 Method for preparing diorganopolysiloxane having a functional group at only one end of the molecular chain Dow Corning Toray Silicone Company, Limited (JP) 1995-11-02 EP claimed
EP-0278157-B1 A RUBBER COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 1993-06-16 EP claimed
US-3993839-A ORGANO-SILOXY TITANIC ACID ESTERS SHINETSU CHEMICAL COMPANY (JA) 1976-11-23 US claimed
US-12550699-B2 Integrated circuit interconnect structure having discontinuous barrier layer and air gap TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2026-02-10 US disclosed
EP-0019674-A1 Process for the production of a hollow catalyst carrier made of transition-alumina Sumitomo Aluminium Smelting Company Limited (JP) 1980-12-10 EP disclosed
US-4143088-A ORGANOSILICON COMPOUND, ORGANOTITANIUM COMPOUND RHONE-POULENC INDUSTRIES (FR) 1979-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12550699-B2 Integrated circuit interconnect structure having discontinuous barrier layer and air gap CTCF, GJB2, ICOSLG TRPA1 526/4885ATM 259/4885ALDH1A1 3863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.