Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400579 | 1.00 | GPR84 (0.48) | GPR84MC4RHTTSMN1; SMN2MMP1 | |
| SCHEMBL11393247 | 1.00 | GPR84 (0.48) | GPR84MC4RHTTSMN1; SMN2MMP1 | |
| SCHEMBL11395840 | 1.00 | GPR84 (0.48) | GPR84MC4RHTTSMN1; SMN2MMP1 | |
| SCHEMBL11399329 | 0.94 | MC4R (0.50) | GPR84MC4RHTTSMN1; SMN2MMP1 | |
| SCHEMBL11399022 | 0.81 | MC4R (0.53) | MC4RSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL11398706 | 0.77 | MC4R (0.44) | MC4RHTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11396158 | 0.73 | MMP1 (0.52) | MC4RSMN1; SMN2MMP1MMP9MMP12 | |
| SCHEMBL223748 | 0.73 | MAPT (0.55) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL11395537 | 0.72 | RAB9A (0.54) | HTTSMN1; SMN2MMP1MMP9MMP12 | |
| SCHEMBL11401028 | 0.72 | MAPT (0.45) | MC4RSMN1; SMN2ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273573-A | Agents for regulating plant growth using 2-thiazolone-5-carboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | disclosed |
| US-3932436-A | 2-Thiazolone-5-carboxylic acid ester fungicidal agents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |