Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 7/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 3/20 | 0.34 |
| ▸ | MC1R | Q01726 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23883211 | 0.73 | DRD2 (0.55) | KCNH2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5820396 | 0.73 | DRD2 (0.55) | KCNH2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL20529619 | 0.71 | TSHR (0.40) | DPP4DPP7DPP8KCNH2OPRM1 | |
| SCHEMBL3676873 | 0.71 | TSHR (0.40) | DPP4DPP7DPP8KCNH2OPRM1 | |
| SCHEMBL10935924 | 0.70 | MC4R (0.41) | OPRD1CCR3MC4RMC1R | |
| SCHEMBL11399203 | 0.68 | DRD2 (0.61) | KCNH2OPRM1OPRK1MC4R | |
| SCHEMBL10677826 | 0.67 | OPRL1 (0.37) | P2RX7OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL10936692 | 0.66 | MC4R (0.43) | CCR3MC4RMC1R | |
| SCHEMBL10530556 | 0.65 | OPRM1 (0.69) | KCNH2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11401962 | 0.63 | CYP2D6 (0.55) | OPRL1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248877-A | ANTIDEPRESSANTS, ANALGESICS, ANTIMIGRAINE AGENTS | SANDOZ LTD. (CH) | 1981-02-03 | — | — | US | claimed |