Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724437 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL22325320 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL10155752 | 0.73 | FLT3 (0.67) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL5160471 | 0.72 | TAS1R3 (0.53) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL9669837 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL9669835 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL8401808 | 0.71 | TP53 (0.70) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL29502855 | 0.71 | MAPT (0.67) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL2775850 | 0.71 | MAPT (0.67) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL155789 | 0.70 | FLT3 (0.74) | ALDH1A1HPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269846-A | BENZOHETEROCYCLIC OXADIAZOLONES AND TRIAZOLONES | USV PHARMACEUTICAL CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |