Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384052 | 0.83 | ALDH1A1 (0.43) | FAAHLMNAALDH1A1 | |
| SCHEMBL11386368 | 0.78 | ALDH1A1 (0.38) | FAAHMEN1CYP2C19RECQLKMT2A | |
| SCHEMBL27621396 | 0.77 | MEN1 (0.36) | FAAHMEN1CYP2C19RECQLKMT2A | |
| SCHEMBL11401129 | 0.77 | TSHR (0.46) | FAAHMEN1KMT2ALMNA | |
| SCHEMBL17011231 | 0.77 | MEN1 (0.33) | MEN1CYP2C19RECQLKMT2ALMNA | |
| SCHEMBL29206695 | 0.76 | LMNA (0.42) | FAAHLMNA | |
| SCHEMBL5269325 | 0.76 | LMNA (0.42) | FAAHLMNA | |
| SCHEMBL28617313 | 0.76 | LMNA (0.42) | FAAHLMNA | |
| SCHEMBL10087852 | 0.75 | LMNA (0.33) | MEN1CYP2C19RECQLKMT2ALMNA | |
| SCHEMBL8830592 | 0.75 | MEN1 (0.37) | MEN1CYP2C19RECQLKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258040-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4060687-A | Cephalosporins having a 3-α substituted alkyl grouping | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |