Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2610011 | 0.80 | MMP1 (0.39) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL823240 | 0.80 | MMP1 (0.39) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL2044655 | 0.80 | MMP1 (0.39) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL13377782 | 0.80 | CYP2C19 (0.37) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL27621396 | 0.78 | MEN1 (0.36) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL27899749 | 0.78 | MMP1 (0.38) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL27684184 | 0.78 | MEN1 (0.36) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL27265848 | 0.78 | ALDH1A1 (0.39) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL7065064 | 0.76 | LMNA (0.41) | MEN1CYP2C19RECQLKMT2AALDH1A1 | |
| SCHEMBL28491797 | 0.76 | MEN1 (0.43) | MEN1CYP2C19RECQLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661153-A | FOR TREATING ALLERGIES, ASTHMA, DERMATITIS, GRAFT REJECTIONS | JAPAN ENERGY CORPORATION (JP) | 1997-08-26 | — | — | US | disclosed |
| WO-1993023410-A1 | NOVEL PLATINUM (IV) DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE ROGER BELLON (FR) | 1993-11-25 | — | — | WO | disclosed |