Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088533 | 0.85 | PTGS2 (0.59) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL7464815 | 0.81 | PTGS2 (0.57) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL10886820 | 0.81 | PTGS2 (0.48) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL7677854 | 0.80 | ABCB11 (0.44) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL7674536 | 0.79 | PTGS2 (0.57) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL11442379 | 0.78 | POLB (0.37) | SMN1; SMN2LMNAALDH1A1HSD17B10POLB | |
| SCHEMBL11062777 | 0.77 | CA12 (0.45) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL11811352 | 0.77 | ALDH1A1 (0.46) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL11810469 | 0.77 | ABCB11 (0.55) | ABCB11PTGS2SMN1; SMN2LMNATSHR | |
| SCHEMBL7676885 | 0.77 | PTGS2 (0.55) | ABCB11PTGS2SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032048-A1 | Pyrroloylpyrrole derivatives, processes for their preparation and their use | BEECHAM GROUP PLC (GB) | 1981-07-15 | — | — | EP | disclosed |