Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410813 | 0.85 | ACHE (0.44) | ALDH1A1ACHEMTNR1ANPC1POLB | |
| SCHEMBL11408975 | 0.85 | ACHE (0.44) | KMT2AALDH1A1HPGDACHELMNA | |
| Hydrochloric Acid SCHEMBL11409887 | 0.84 | ACHE (0.43) | ALDH1A1ACHEMTNR1A | |
| SCHEMBL11407590 | 0.83 | ACHE (0.44) | KMT2AACHELMNASMN1; SMN2HTT | |
| SCHEMBL11410612 | 0.83 | LMNA (0.41) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11409003 | 0.82 | ACHE (0.43) | KMT2AACHELMNASMN1; SMN2HTT | |
| SCHEMBL11410559 | 0.80 | TAOK1 (0.43) | KMT2AMEN1ACHEMTNR1ASMN1; SMN2 | |
| SCHEMBL11414455 | 0.79 | LMNA (0.47) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11409248 | 0.77 | ACHE (0.42) | ACHE | |
| SCHEMBL11418339 | 0.77 | NPC1 (0.46) | MAPTKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55057546-A | — | — | None | — | — | JP | disclosed |
| JP-S5557546-A | DERIVATIVE OF TETRALIN | TORII YAKUHIN KK | 1980-04-28 | — | — | JP | disclosed |