Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28253503 | 1.00 | — | — | |
| Iodide SCHEMBL3927326 | 0.82 | CA4 (0.33) | — | |
| Iodide SCHEMBL750 | 0.82 | — | — | |
| Iodide SCHEMBL18707 | 0.82 | — | — | |
| Iodide SCHEMBL7209603 | 0.82 | — | — | |
| Iodide SCHEMBL6131651 | 0.82 | — | — | |
| Iodide SCHEMBL9131243 | 0.82 | — | — | |
| Iodide SCHEMBL4656335 | 0.82 | — | — | |
| Iodide SCHEMBL11231929 | 0.67 | — | — | |
| Iodide SCHEMBL10795859 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050962-A1 | IMIDAZO[1,2-A]PYRIDINES AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR TREATING CARDIOVASCULAR DISEASES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | US | disclosed |
| EP-0035357-A1 | 2-Methylcephalosporins and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-09-09 | — | — | EP | disclosed |