Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582891 | 0.82 | ALDH1A1 (0.69) | GPR35ALDH1A1GAAL3MBTL1MAPT | |
| Lodoxamide Ethyl SCHEMBL667976 | 0.81 | GPR35 (1.00) | GPR35ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL9364621 | 0.81 | ALDH1A1 (0.56) | GPR35ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL11391689 | 0.79 | GPR35 (0.62) | GPR35ALDH1A1GAA | |
| SCHEMBL9369972 | 0.79 | ALDH1A1 (0.60) | GPR35ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL11615055 | 0.79 | GPR35 (0.53) | GPR35ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL11671049 | 0.78 | GPR35 (0.58) | GPR35ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL11390592 | 0.76 | GPR35 (0.68) | GPR35ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL9364832 | 0.76 | GPR35 (0.60) | GPR35ALDH1A1GAAMAPTTHRA | |
| SCHEMBL11571030 | 0.75 | GPR35 (0.74) | GPR35ALDH1A1GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281151-A | ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS | THE UPJOHN COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4186127-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| US-4159278-A | PROPHYAXIS, ANTIALLERGENS, SENSITIZATION | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4095028-A | PROPHYLAXIS, ALLERGIES | THE UPJOHN COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4089973-A | Cyano phenylene dioxamic acid compounds used in the treatment of allergy | THE UPJOHN COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-3993679-A | ANTIALLERGY | THE UPJOHN COMPANY (US) | 1976-11-23 | — | — | US | disclosed |