Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349168 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAAMAPK1MEN1KMT2A | |
| SCHEMBL8521071 | 0.72 | CYP1A2 (0.44) | ALDH1A1HAVCR2IDH1KMT2AL3MBTL1 | |
| SCHEMBL11401212 | 0.68 | NQO2 (0.35) | ALDH1A1HAVCR2IDH1MEN1KMT2A | |
| SCHEMBL8957061 | 0.68 | IDH1 (0.37) | ALDH1A1IDH1KMT2ACYP1A2KDM4E | |
| SCHEMBL15360209 | 0.65 | LMNA (0.41) | ALDH1A1GAAMEN1KMT2ATSHR | |
| SCHEMBL11527661 | 0.65 | NQO2 (0.37) | HAVCR2IDH1KMT2ACYP1A2KDM4E | |
| SCHEMBL13827862 | 0.65 | PLA2G7 (0.34) | ALDH1A1HAVCR2IDH1MEN1KMT2A | |
| SCHEMBL22579369 | 0.64 | MEN1 (0.43) | IDH1MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL11530183 | 0.64 | GAA (0.34) | GAAHAVCR2IDH1KMT2AKDM4E | |
| SCHEMBL8070172 | 0.63 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55104266-A | — | — | None | — | — | JP | disclosed |
| JP-S55104266-A | NOVEL PYRIDONE DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1980-08-09 | — | — | JP | disclosed |