Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403987 | 0.90 | LMNA (0.54) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL4837127 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL3495616 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL11390332 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL4833579 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL11391949 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL27626394 | 0.74 | CNR1 (0.44) | — | |
| SCHEMBL5907322 | 0.73 | PTGS2 (0.47) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL5907346 | 0.72 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL7912407 | 0.71 | NPC1 (0.65) | MEN1KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258047-A | ANALGESICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| EP-0014847-A1 | Pyrazole derivatives, pharmaceutical preparations containing them and process for their production | MERCK PATENT GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |