SCHEMBL1140106

SCHEMBL1140106

C=CC(O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.61
TK2 O00142 2/20 0.59
SLC28A1 O00337 1/20 0.52
SLC28A2 O43868 1/20 0.52
SLC29A1 Q99808 1/20 0.52
SLC28A3 Q9HAS3 1/20 0.52
DNPH1 O43598 1/20 0.46
P2RY2 P41231 4/20 0.45
HPGD P15428 1/20 0.42
MAPT P10636 1/20 0.42
CDA P32320 1/20 0.42
P2RY6 Q15077 1/20 0.41
P2RY14 Q15391 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547183 0.88 PYGM (0.60) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL8369203 0.85 PYGM (0.65) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL13518430 0.84 PYGM (0.55) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL40820 0.84 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18503568 0.84 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18512917 0.84 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18512919 0.84 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL40819 0.84 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL23083301 0.83 TK2 (0.74) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2587226 0.83 TK2 (0.74) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4023233-A2 OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF Sator Therapeutics LLC (US) 2022-07-06 EP claimed
US-20220088097-A1 OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF SATOR THERAPEUTICS 2022-03-24 US claimed
EP-3518947-A1 OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF Sator Therapeutics LLC (US) 2019-08-07 EP claimed
WO-2018064134-A1 OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF Sator Therapeutics LLC (US) 2018-04-05 WO claimed
US-20180085411-A1 OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF SATOR THERAPEUTICS 2018-03-29 US claimed
EP-0948256-A4 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA UNIV WASHINGTON (US) 2007-10-24 EP claimed
US-20050187180-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA UNIVERSITY OF WASHINGTON (US) 2005-08-25 US claimed
US-6887707-B2 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA UNIVERSITY OF WASHINGTON (US) 2005-05-03 US claimed
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-06-26 US claimed
US-6063628-A Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA UNIVERSITY OF WASHINGTON (US) 2000-05-16 US claimed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP claimed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO claimed
US-20240052357-A1 AUTONOMOUS INDUCIBLE DIRECTED EVOLUTION OF COMPLEX PATHWAYS NORTH CAROLINA STATE UNIVERSITY 2024-02-15 US disclosed
CN-117085047-A Optimized oncolytic viruses and uses thereof 萨特治疗学有限公司 2023-11-21 CN disclosed
EP-3518947-B1 OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF Sator Therapeutics LLC (US) 2023-07-05 EP disclosed
CN-109982708-B Optimized oncolytic viruses and uses thereof 萨特治疗学有限公司 2023-05-23 CN disclosed
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-06-26 US disclosed
US-6063628-A Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA UNIVERSITY OF WASHINGTON (US) 2000-05-16 US disclosed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP disclosed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA SAMHD1, BCDIN3D, DCTD PYGM 3753/4885TK2 279/4885SLC28A1 891/4885
US-20050187180-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA SAMHD1, BCDIN3D, DCTD PYGM 3753/4885TK2 279/4885SLC28A1 891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.