Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 5/20 | 0.74 |
| ▸ | PYGM | P11217 | 3/20 | 0.66 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786493 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13597474 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13447935 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13413052 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1532596 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1627679 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13252708 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL2587226 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1532595 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL7571099 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12038377-B2 | Devices, compositions and methods for imaging with Raman scattering | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-07-16 | — | — | US | disclosed |
| US-20210068663-A1 | DEVICES, COMPOSITIONS AND METHODS FOR IMAGING WITH RAMAN SCATTERING AND FOR SUPER-MULTIPLEX VIBRATIONAL IMAGING | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12038377-B2 | Devices, compositions and methods for imaging with Raman scattering | SCARB1, TTR, GLS2 | TK2 2522/4885PYGM 246/4885SLC28A1 2335/4885 |
| US-20210068663-A1 | DEVICES, COMPOSITIONS AND METHODS FOR IMAGING WITH RAMAN SCATTERING AND FOR SUPER-MULTIPLEX VIBRATIONAL IMAGING | VCL, TTR, VSIR | TK2 3611/4885PYGM 770/4885SLC28A1 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.