Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401467 | 1.00 | TMEM97 (0.47) | TMEM97HTR2AHTR2CHRH1HTR2B | |
| Hydrochloric Acid SCHEMBL11321319 | 0.98 | TMEM97 (0.46) | TMEM97HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL12622887 | 0.84 | TMEM97 (0.40) | TMEM97SIGMAR1OPRM1ADRA2A | |
| SCHEMBL11323060 | 0.84 | TMEM97 (0.46) | TMEM97HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL26011230 | 0.81 | SIGMAR1 (0.42) | TMEM97SIGMAR1ADRA2A | |
| SCHEMBL11323825 | 0.81 | OPRD1 (0.46) | TMEM97HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL11323828 | 0.81 | OPRD1 (0.46) | TMEM97HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL11323983 | 0.80 | TMEM97 (0.44) | TMEM97HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL11323986 | 0.80 | TMEM97 (0.44) | TMEM97HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL29190477 | 0.79 | TMEM97 (0.41) | TMEM97SIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263317-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-04-21 | — | — | US | claimed |