Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12622887 | 0.84 | TMEM97 (0.40) | TMEM97SIGMAR1ADRA2A | |
| SCHEMBL2360287 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ADRA2A | |
| SCHEMBL3406036 | 0.83 | SIGMAR1 (0.37) | TMEM97SIGMAR1ADRA2A | |
| SCHEMBL736557 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ADRA2A | |
| SCHEMBL24203981 | 0.81 | MEN1 (0.37) | SIGMAR1ADRA2A | |
| SCHEMBL30376318 | 0.81 | MEN1 (0.37) | SIGMAR1ADRA2A | |
| SCHEMBL11864088 | 0.81 | SIGMAR1 (0.54) | SIGMAR1ADRA2A | |
| SCHEMBL17027449 | 0.80 | SIGMAR1 (0.36) | TMEM97SIGMAR1ADRA2A | |
| SCHEMBL11401467 | 0.79 | TMEM97 (0.47) | TMEM97SIGMAR1ADRA2A | |
| SCHEMBL11401469 | 0.79 | TMEM97 (0.47) | TMEM97SIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261557-A | Cyclic cyanoketene derivatives as KEAP1 modulators | 默沙东有限责任公司 | 2023-06-13 | — | — | CN | disclosed |