Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MYLK | Q15746 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | FER | P16591 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905704 | 0.81 | KMT2A (0.40) | CDK2KMT2AKDM4EPARP1MEN1 | |
| SCHEMBL10865297 | 0.79 | KMT2A (0.42) | CDK2KMT2AKDM4EPARP1ALDH1A1 | |
| SCHEMBL11838515 | 0.78 | KMT2A (0.38) | CDK2KMT2APARP1MEN1ALDH1A1 | |
| SCHEMBL21104441 | 0.74 | CDK2 (0.47) | CDK2KMT2APARP1ALDH1A1POLB | |
| SCHEMBL24317500 | 0.69 | CDK2 (0.44) | CDK2CHEK1KMT2AKDM4EPARP1 | |
| SCHEMBL7936537 | 0.69 | RAD52 (0.44) | KMT2AKDM4EPARP1MEN1TDP1 | |
| SCHEMBL11318564 | 0.69 | KMT2A (0.45) | CDK2KMT2APARP1MEN1TDP1 | |
| SCHEMBL11204216 | 0.68 | PARP1 (0.58) | CDK2KMT2AKDM4EPARP1MEN1 | |
| SCHEMBL27936606 | 0.67 | ALDH1A1 (0.53) | KMT2AKDM4EPARP1MEN1TDP1 | |
| SCHEMBL11210705 | 0.67 | PARP1 (0.56) | CDK2KMT2AKDM4EPARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55142056-A | — | — | None | — | — | JP | disclosed |
| JP-S55142056-A | PREPARATION OF BASIC DYE | MITSUBISHI CHEM IND LTD | 1980-11-06 | — | — | JP | disclosed |