Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.36 |
| ▸ | CDK4 | P11802 | 6/20 | 0.36 |
| ▸ | CCND1 | P24385 | 6/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905704 | 0.87 | KMT2A (0.40) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL10865297 | 0.85 | KMT2A (0.42) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL21104441 | 0.80 | CDK2 (0.47) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL24317500 | 0.78 | CDK2 (0.44) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL11403548 | 0.78 | CDK2 (0.46) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL11318564 | 0.75 | KMT2A (0.45) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL7936537 | 0.75 | RAD52 (0.44) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL7537819 | 0.73 | ALDH1A1 (0.43) | KMT2APARP1ALDH1A1POLBBLM | |
| SCHEMBL5271087 | 0.73 | CES1 (0.55) | KMT2APOLBBLMCES1MEN1 | |
| SCHEMBL28709694 | 0.72 | GRIA1 (0.38) | KMT2APARP1CDK4CCND1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |