Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404147 | 0.87 | MAPT (0.51) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL11410190 | 0.85 | G6PD (0.56) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL11414123 | 0.84 | ALDH1A1 (0.60) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL11406439 | 0.81 | G6PD (0.60) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL11405206 | 0.80 | G6PD (0.53) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL11414206 | 0.77 | G6PD (0.51) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL11406270 | 0.77 | G6PD (0.60) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL11411200 | 0.77 | G6PD (0.47) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL2243835 | 0.77 | PTGS1 (0.53) | G6PDMAPTALDH1A1ALOX15TSHR | |
| SCHEMBL12355310 | 0.77 | PTGS1 (0.53) | G6PDMAPTALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |