Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454448 | 1.00 | CSNK1E (0.41) | CSNK1ELMNAALDH1A1PAX8MEN1 | |
| SCHEMBL1454798 | 1.00 | CSNK1E (0.41) | CSNK1ELMNAALDH1A1PAX8MEN1 | |
| SCHEMBL1455367 | 1.00 | CSNK1E (0.41) | CSNK1ELMNAALDH1A1PAX8MEN1 | |
| SCHEMBL1455081 | 0.98 | LMNA (0.42) | CSNK1ELMNAALDH1A1PAX8MEN1 | |
| SCHEMBL1455005 | 0.92 | PPARG (0.43) | LMNAALDH1A1PAX8ALOX5PPARG | |
| SCHEMBL1454709 | 0.84 | MAOA (0.41) | LMNAALDH1A1PAX8ALOX5PPARG | |
| SCHEMBL10473468 | 0.82 | MAOA (0.40) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1454990 | 0.82 | LMNA (0.36) | LMNAALDH1A1PAX8ALOX5PPARG | |
| SCHEMBL1454217 | 0.82 | LMNA (0.36) | LMNAALDH1A1PAX8ALOX5PPARG | |
| SCHEMBL7241349 | 0.81 | LMNA (0.43) | CSNK1ELMNAALDH1A1PAX8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021637-A1 | Amidothiol derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1981-01-07 | — | — | EP | disclosed |