Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455081 | 0.94 | LMNA (0.42) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL11404752 | 0.92 | CSNK1E (0.41) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1454448 | 0.92 | CSNK1E (0.41) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1455367 | 0.92 | CSNK1E (0.41) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1454798 | 0.92 | CSNK1E (0.41) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1454709 | 0.88 | MAOA (0.41) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1454990 | 0.85 | LMNA (0.36) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1454217 | 0.85 | LMNA (0.36) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1455148 | 0.83 | L3MBTL1 (0.38) | PPARGALOX5PPARALMNAPAX8 | |
| SCHEMBL1453177 | 0.82 | L3MBTL1 (0.37) | PPARGALOX5PPARALMNAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910617-B2 | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound | SANKYO COMPANY, LIMITED (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20070191468-A1 | Amino alcohol compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1733724-A1 | AMINO ALCOHOL COMPOUND | Sankyo Company, Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-0021637-A1 | Amidothiol derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191468-A1 | Amino alcohol compound | ADH1A, ADH1C, BCAT1 | PPARG 388/4885ALOX5 1019/4885PPARA 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.