Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418654 | 0.84 | SMN1; SMN2 (0.57) | TSHRESR1ESR2SMN1; SMN2MEN1 | |
| SCHEMBL11415282 | 0.84 | TSHR (0.43) | TSHRSMN1; SMN2MEN1ALOX15KMT2A | |
| SCHEMBL11411119 | 0.83 | ESR2 (0.47) | TSHRESR1ESR2SMN1; SMN2SIGMAR1 | |
| SCHEMBL11408254 | 0.83 | PKM (0.43) | TSHRSMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL11404073 | 0.83 | HTR3E (0.43) | TSHRESR1ESR2SMN1; SMN2MEN1 | |
| SCHEMBL31285548 | 0.80 | TSHR (0.48) | TSHRSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL26325448 | 0.80 | TSHR (0.48) | TSHRSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11404995 | 0.77 | RAB9A (0.46) | TSHRSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL6025442 | 0.75 | GAA (0.57) | TSHRSMN1; SMN2MEN1ALOX15KMT2A | |
| SCHEMBL6025444 | 0.75 | GAA (0.57) | TSHRSMN1; SMN2MEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |