Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494489 | 0.72 | METAP1 (0.40) | SRD5A1METAP1CYP3A4DDB1CRBN | |
| SCHEMBL13899831 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL10803732 | 0.66 | METAP1 (0.36) | CCR6HSP90AA1MITFMETAP1CYP3A4 | |
| SCHEMBL12765142 | 0.65 | HSP90AA1 (0.46) | CCR6HSP90AA1MITFMETAP1CYP3A4 | |
| SCHEMBL2125675 | 0.64 | METAP1 (0.71) | METAP1THRATHRB | |
| SCHEMBL8003063 | 0.64 | METAP1 (0.71) | METAP1THRATHRB | |
| Hydrochloric Acid SCHEMBL9301348 | 0.64 | HSP90AA1 (0.48) | CCR6HSP90AA1MITFMETAP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL2125507 | 0.62 | METAP1 (0.72) | METAP1THRATHRB | |
| SCHEMBL9278025 | 0.61 | GLA (0.41) | METAP1CRBN | |
| SCHEMBL3965498 | 0.61 | METAP1 (0.41) | CCR6HSP90AA1MITFMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55085565-A | — | — | None | — | — | JP | disclosed |
| JP-S5585565-A | 5-OXO-3,4,5,6,7,8-HEXAHYDROCARBOSTYRYL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1980-06-27 | — | — | JP | disclosed |