Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 4/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9301348 | 0.98 | HSP90AA1 (0.48) | HSP90AA1MITFCCR6ADRA2AADRA2B | |
| SCHEMBL13899831 | 0.71 | — | — | |
| SCHEMBL3965498 | 0.66 | METAP1 (0.41) | HSP90AA1MITFCCR6METAP1 | |
| SCHEMBL10426987 | 0.66 | ADRA1D (0.45) | HSP90AA1MITFADRA1DADRA1AADRA1B | |
| SCHEMBL8003063 | 0.66 | METAP1 (0.71) | METAP1THRATHRB | |
| SCHEMBL2125675 | 0.66 | METAP1 (0.71) | METAP1THRATHRB | |
| SCHEMBL11723357 | 0.65 | THRA (0.52) | CCR6METAP1THRATHRB | |
| SCHEMBL11405141 | 0.65 | CCR6 (0.40) | HSP90AA1MITFCCR6ADRA2AADRA2B | |
| SCHEMBL14229576 | 0.64 | CCR6 (0.40) | HSP90AA1MITFCCR6CYP3A4SMN1; SMN2 | |
| SCHEMBL6865770 | 0.64 | HTR6 (0.39) | HSP90AA1MITFCCR6SMN1; SMN2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058258-C | 2-[N-substituted amine alkyl]-5-(E)-alkylmethylene or phenylmethylene cyclopentanone derivatives and applications | SHENYANG COLLEGE OF PAHRMACY (CN) | 2000-11-08 | — | — | CN | claimed |
| US-8415505-B2 | 2-methylene-5-substituted-methylenecyclopentanone derivatives and use thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2013-04-09 | — | — | US | disclosed |
| US-20110060054-A1 | 2-METHYLENE-5-SUBSTITUTED-METHYLENECYCLOPENTANONE DERIVATIVES AND USE THEREOF | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060054-A1 | 2-METHYLENE-5-SUBSTITUTED-METHYLENECYCLOPENTANONE DERIVATIVES AND USE THEREOF | BRCA1, KLK3, DPYD | HSP90AA1 2967/4885MITF 3345/4885CCR6 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.