Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 5/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997701 | 0.90 | METAP1 (0.39) | METAP1CCR6MITFHSP90AA1 | |
| SCHEMBL12721211 | 0.88 | METAP1 (0.38) | METAP1CCR6MITFHSP90AA1 | |
| SCHEMBL12493861 | 0.81 | METAP1 (0.34) | METAP1CCR6MITFHSP90AA1 | |
| SCHEMBL12494213 | 0.78 | METAP1 (0.36) | METAP1CCR6MITFHSP90AA1 | |
| SCHEMBL6741340 | 0.78 | METAP1 (0.35) | METAP1CCR6MITFHSP90AA1 | |
| SCHEMBL13899831 | 0.75 | — | — | |
| SCHEMBL6869112 | 0.73 | METAP1 (0.39) | METAP1CCR6 | |
| SCHEMBL14141207 | 0.72 | ACE (0.45) | — | |
| SCHEMBL6865770 | 0.72 | HTR6 (0.39) | METAP1CCR6MITFHSP90AA1 | |
| SCHEMBL4631245 | 0.72 | HTR6 (0.39) | METAP1CCR6MITFHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695186-B2 | Alicyclic diepoxy compound having bis-spironorbornane structure, method for producing the same, and use thereof | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9695186-B2 | Alicyclic diepoxy compound having bis-spironorbornane structure, method for producing the same, and use thereof | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9669016-B2 | Antiparasitic effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669016-B2 | Antiparasitic effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-06-06 | — | — | US | disclosed |
| EP-3135677-A1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING SAME, AND USE FOR SAME | JX Nippon Oil & Energy Corporation (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-20170044179-A1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING THE SAME, AND USE THEREOF | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |
| US-20170044179-A1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING THE SAME, AND USE THEREOF | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |
| US-20160303105-A1 | Antiparasitic Effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-10-20 | — | — | US | disclosed |
| US-20160303105-A1 | Antiparasitic Effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-10-20 | — | — | US | disclosed |
| US-20150290183-A1 | ANTIPARASITIC EFFECT OF BIS[3,5-BIS(BENZYLIDENE)-4-OXO-1-PIPERIDINYL]AMIDE DERIVATIVES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2015-10-15 | — | — | US | disclosed |
| US-20150290183-A1 | ANTIPARASITIC EFFECT OF BIS[3,5-BIS(BENZYLIDENE)-4-OXO-1-PIPERIDINYL]AMIDE DERIVATIVES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2015-10-15 | — | — | US | disclosed |
| EP-1572197-B1 | 4- 1- (SULFONYL) -1H-INDOL-2-YL)-4- (HYDROXY) -CYCLOHEXA-2,5-DIENONE COMPOUNDS AND ANALOGS THEREOF AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2009-07-29 | — | — | EP | disclosed |
| EP-1572197-A1 | 4- 1- (SULFONYL) -1H-INDOL-2-YL)-4- (HYDROXY) -CYCLOHEXA-2,5-DIENONE COMPOUNDS AND ANALOGS THEREOF AS THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056361-A1 | 4-(1-(SULFONYL)-1H-INDOL-2-YL)-4-(HYDROXY)-CYCLOHEXA-2,5-DIENONE COMPOUNDS AND ANALOGS THEREOF AS THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290183-A1 | ANTIPARASITIC EFFECT OF BIS[3,5-BIS(BENZYLIDENE)-4-OXO-1-PIPERIDINYL]AMIDE DERIVATIVES | PDF, GLS2, OXA1L | METAP1 1335/4885CCR6 1932/4885MITF 3945/4885 |
| US-20170044179-A1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING THE SAME, AND USE THEREOF | DHCR7, HSD17B7, CYP17A1 | METAP1 4582/4885CCR6 2828/4885MITF 4448/4885 |
| US-20160303105-A1 | Antiparasitic Effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives | PDF, GLS2, OXA1L | METAP1 1335/4885CCR6 1932/4885MITF 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.