Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | CCR2 | P41597 | 4/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398514 | 0.88 | HTT (0.69) | HTTTTRCCR2GRIK1KDM4E | |
| SCHEMBL48961 | 0.85 | MRGPRX4 (0.64) | TTRKDM4EGAAALDH1A1HPGD | |
| SCHEMBL30100412 | 0.85 | MRGPRX4 (0.64) | TTRKDM4EGAAALDH1A1HPGD | |
| SCHEMBL11483642 | 0.85 | CCR2 (0.55) | HTTCCR2GAAALDH1A1HPGD | |
| SCHEMBL11484178 | 0.84 | ALDH1A1 (0.58) | TTRCCR2GAAALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7210817 | 0.84 | MRGPRX4 (0.62) | TTRKDM4EGAAALDH1A1HPGD | |
| SCHEMBL11091873 | 0.83 | CA1 (0.54) | TTRCCR2GRIK1GAAALDH1A1 | |
| SCHEMBL3384527 | 0.82 | HTT (1.00) | HTTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL22891351 | 0.81 | CYP1A2 (0.57) | HTTTTRCCR2KDM4EGAA | |
| SCHEMBL3630423 | 0.80 | MRGPRX4 (0.58) | TTRGRIK1GAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242121-A | USING A PHENOXYBENZOIC ACID, ITS ESTER OR SALT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-12-30 | — | — | US | claimed |
| US-4268514-A | ANALGESICS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | disclosed |