Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414189 | 0.83 | RAB9A (0.58) | RAB9ANPC1PKMMAPK1CYP1A2 | |
| SCHEMBL11414186 | 0.83 | RAB9A (0.58) | RAB9ANPC1PKMMAPK1CYP1A2 | |
| SCHEMBL11416377 | 0.81 | RAB9A (0.49) | RAB9ANPC1PKMMAPK1CYP1A2 | |
| SCHEMBL11416379 | 0.81 | RAB9A (0.49) | RAB9ANPC1PKMMAPK1CYP1A2 | |
| SCHEMBL11410693 | 0.81 | ALDH1A1 (0.46) | RAB9ANPC1PKMMAPK1MAPT | |
| SCHEMBL11403669 | 0.80 | CHRM5 (0.55) | RAB9ANPC1PKMCYP1A2CYP2D6 | |
| SCHEMBL5074324 | 0.80 | CYP2C9 (0.52) | RAB9ANPC1PKMBLMMAPT | |
| SCHEMBL7636431 | 0.80 | CYP2C9 (0.52) | RAB9ANPC1PKMBLMMAPT | |
| SCHEMBL11407057 | 0.80 | NFE2L2 (0.49) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL11403855 | 0.78 | CA12 (0.48) | RAB9ANPC1PKMMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |