Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.55 |
| ▸ | NAAA | Q02083 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 8/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695608 | 0.83 | MEN1 (0.46) | CTSLNAAAASAH1 | |
| SCHEMBL11500430 | 0.82 | MEN1 (0.44) | CTSLNAAA | |
| SCHEMBL10544954 | 0.81 | CTSL (0.59) | CTSLNAAACTSSCTSKASAH1 | |
| SCHEMBL11404293 | 0.80 | MEN1 (0.38) | CTSLNAAA | |
| SCHEMBL10541442 | 0.80 | CTSL (0.73) | CTSLNAAACTSSCTSKASAH1 | |
| SCHEMBL10544614 | 0.79 | CTSL (0.65) | CTSLNAAACTSSCTSKASAH1 | |
| SCHEMBL10544611 | 0.78 | CTSL (0.66) | CTSLNAAACTSSCTSKCTSB | |
| SCHEMBL10765931 | 0.78 | MAPT (0.41) | CTSLNAAAASAH1 | |
| SCHEMBL10545315 | 0.77 | MAPT (0.50) | CTSLNAAAASAH1 | |
| SCHEMBL10545089 | 0.76 | CTSL (0.65) | CTSLNAAACTSSCTSKASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |