Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695608 | 0.91 | MEN1 (0.46) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11404293 | 0.84 | MEN1 (0.38) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10545315 | 0.83 | MAPT (0.50) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11405493 | 0.82 | CTSL (0.55) | CTSLNAAA | |
| SCHEMBL10545391 | 0.82 | MAPT (0.43) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10546201 | 0.81 | MEN1 (0.43) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10765931 | 0.81 | MAPT (0.41) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10547403 | 0.81 | MAPT (0.44) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10545073 | 0.81 | MEN1 (0.42) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11065314 | 0.81 | MEN1 (0.42) | MEN1KMT2ACCKBRMAPTPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |