Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | G6PD | P11413 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492230 | 0.93 | G6PD (0.61) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL9492224 | 0.93 | G6PD (0.61) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL9492237 | 0.93 | G6PD (0.61) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL19875637 | 0.84 | ALDH1A1 (0.80) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL9491155 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL9491152 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11408231 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11409543 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL264278 | 0.80 | ALDH1A1 (0.73) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL12349218 | 0.80 | ALDH1A1 (0.73) | ALDH1A1MAPTALOX15TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |