SCHEMBL264278

SCHEMBL264278

[O-][N+](=Cc1ccccc1)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.73
MAPT P10636 8/20 0.73
G6PD P11413 3/20 0.73
ALOX15 P16050 2/20 0.73
TSHR P16473 1/20 0.73
RECQL P46063 1/20 0.73
NPC1 O15118 5/20 0.59
RAB9A P51151 4/20 0.59
HSD17B10 Q99714 2/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
LMNA P02545 1/20 0.44
NFE2L2 Q16236 1/20 0.44
FBP1 P09467 2/20 0.42
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL264277 1.00 ALDH1A1 (0.73) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL12349218 1.00 ALDH1A1 (0.73) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL19875637 0.95 ALDH1A1 (0.80) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL16634847 0.89 ALDH1A1 (0.76) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL16634831 0.89 ALDH1A1 (0.76) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL11405083 0.85 G6PD (0.67) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL11406588 0.85 ALDH1A1 (1.00) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL2248023 0.85 G6PD (0.67) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL12355268 0.85 G6PD (1.00) ALDH1A1MAPTG6PDALOX15TSHR
SCHEMBL11408998 0.85 G6PD (0.67) ALDH1A1MAPTG6PDALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101405802-A Method of storing holographic data and articles derived therefrom having improved data storage lifetime GEN ELECTRIC (US) 2009-04-08 CN claimed
US-3988159-A Light-sensitive material containing nitrone for forming heat-fixed images AMERICAN CAN COMPANY (US) 1976-10-26 US claimed
US-3988229-A Stabilized photopolymerizable polymeric compositions containing a photoinitiator and a nitrone derivative EASTMAN KODAK COMPANY (US) 1976-10-26 US claimed
CN-120040472-A Method for synthesizing arylthiopyrano [3,2-e ] [1,2] oxazine compound through photocatalysis 南京工业大学 2025-05-27 CN disclosed
CN-110963943-B Method for synthesizing arylamidine compound through decarboxylation reaction one-pot method 山东师范大学 2022-08-19 CN disclosed
CN-110981808-B Method for synthesizing diastereomer 2-imidazolone compound by silver and alkali concerted catalysis 山东师范大学 2021-01-08 CN disclosed
CN-110981808-A Method for synthesizing diastereomer 2-imidazolone compound by silver and alkali concerted catalysis 山东师范大学 2020-04-10 CN disclosed
CN-110963943-A Method for synthesizing aryl amidine compound through decarboxylation reaction one-pot method 山东师范大学 2020-04-07 CN disclosed
US-10040316-B2 Rubber composition for tire tread, and studless tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2018-08-07 US disclosed
US-20180118856-A1 RUBBER COMPOSITION AND TIRE THE YOKOHAMA RUBBER CO., LTD. (JP) 2018-05-03 US disclosed
US-20180118653-A1 METHOD FOR PURIFICATION OF A AROMATIC DIACID OR THE CORRESPONDING ANHYDRIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-05-03 US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed
US-3991261-A POLYMERIZABLE (METH)ACRYLIC ESTER AND HYDROCARBON PEROXIDE CATALYST; STORAGE STABLE HENKEL & CIE G.M.B.H. (DT) 1976-11-09 US disclosed
US-3988159-A Light-sensitive material containing nitrone for forming heat-fixed images AMERICAN CAN COMPANY (US) 1976-10-26 US disclosed
US-3988229-A Stabilized photopolymerizable polymeric compositions containing a photoinitiator and a nitrone derivative EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118653-A1 METHOD FOR PURIFICATION OF A AROMATIC DIACID OR THE CORRESPONDING ANHYDRIDES DDC, HPD, ACMSD ALDH1A1 125/4885MAPT 2259/4885G6PD 411/4885
US-10040316-B2 Rubber composition for tire tread, and studless tire TRHDE, TRAFD1, BOLA2; BOLA2B ALDH1A1 2899/4885MAPT 940/4885G6PD 3294/4885
US-20180118856-A1 RUBBER COMPOSITION AND TIRE TIPRL, TRRAP, WDR82 ALDH1A1 3913/4885MAPT 4212/4885G6PD 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.