SCHEMBL11406428

SCHEMBL11406428

O=C1NC(=O)N([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)C(O)C1F

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
UMPS P11172 5/20 0.50
FBP1 P09467 2/20 0.49
DNPH1 O43598 1/20 0.47
ATIC P31939 2/20 0.45
TAS1R3 Q7RTX0 2/20 0.45
TAS1R1 Q7RTX1 2/20 0.45
HPRT1 P00492 1/20 0.44
P2RY2 P41231 2/20 0.44
P2RY6 Q15077 2/20 0.44
IMPDH2 P12268 2/20 0.44
GART P22102 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11406434 1.00 UMPS (0.50) UMPSFBP1DNPH1ATICTAS1R3
SCHEMBL10880866 0.81 CDA (0.47)
SCHEMBL10880846 0.81 CDA (0.47)
SCHEMBL31685403 0.74 FBP1 (0.46) UMPSFBP1DNPH1ATICTAS1R3
SCHEMBL3469594 0.73 HPRT1 (0.51) UMPSFBP1DNPH1ATICTAS1R3
SCHEMBL11758791 0.72 CDA (0.62) UMPSFBP1DNPH1ATICHPRT1
SCHEMBL11755358 0.72 CDA (0.62) UMPSFBP1DNPH1ATICHPRT1
SCHEMBL11178912 0.71 HPRT1 (0.53) UMPSFBP1DNPH1ATICTAS1R3
SCHEMBL7269691 0.70 FBP1 (0.50) UMPSFBP1DNPH1ATICTAS1R3
SCHEMBL19370845 0.70 FBP1 (0.50) UMPSFBP1DNPH1ATICTAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55028925-A None JP disclosed
JP-S5528925-A DIHYDROURIDYLIC ACID DERIVATIVE AND ITS PREPARATION MITSUI TOATSU CHEM INC 1980-02-29 JP disclosed