Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399746 | 0.81 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL22583527 | 0.79 | NQO1 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8623554 | 0.79 | CHRM2 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11402766 | 0.78 | ALDH1A1 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL16503961 | 0.70 | LMNA (0.41) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL11397020 | 0.70 | KDM4E (0.43) | NPC1ELANERAB9AL3MBTL1CASP3 | |
| SCHEMBL11398940 | 0.69 | NPC1 (0.42) | NPC1ELANERAB9AL3MBTL1CASP3 | |
| SCHEMBL28133648 | 0.67 | MAPKAPK2 (0.35) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL12193372 | 0.67 | CYP19A1 (0.46) | NPC1ELANERAB9AL3MBTL1CASP3 | |
| SCHEMBL12457974 | 0.67 | MAPT (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267327-A | FOR USE IN LOWERING LIPID, TRIGLYCERIDE AND CHOLESTEROL LEVELS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-05-12 | — | — | US | disclosed |