Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399746 | 0.80 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11406583 | 0.79 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL31245536 | 0.76 | BACE1 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL21957976 | 0.76 | BACE1 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30575331 | 0.71 | KDM4E (0.41) | NPC1KMT2ACYP1A2L3MBTL1KDM4E | |
| SCHEMBL13806634 | 0.71 | KDM4E (0.41) | NPC1KMT2ACYP1A2L3MBTL1KDM4E | |
| SCHEMBL31245549 | 0.69 | MAPT (0.43) | NPC1KMT2ACYP1A2L3MBTL1KDM4E | |
| SCHEMBL21958048 | 0.69 | MAPT (0.43) | NPC1KMT2ACYP1A2L3MBTL1KDM4E | |
| SCHEMBL30575324 | 0.69 | LPL (0.34) | CHRM2CHRM1CHRM3NPC1KMT2A | |
| SCHEMBL11397020 | 0.69 | KDM4E (0.43) | NPC1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638559-B1 | PYRAZINE DERIVATIVE | KOEI CHEMICAL CO (JP) | 1998-06-17 | — | — | EP | claimed |