Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 5/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175125 | 0.83 | CA2 (0.47) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL108421 | 0.82 | CA2 (1.00) | CA2CDK2CA1CA9F2 | |
| SCHEMBL11407481 | 0.81 | CA2 (0.96) | CA2CDK2CA1CA9F2 | |
| SCHEMBL9138970 | 0.79 | CDK2 (0.78) | CA2CDK2CA1CA9LDHA | |
| SCHEMBL17380708 | 0.74 | CA2 (0.67) | CA2CDK2CA1CA9LDHA | |
| SCHEMBL1803500 | 0.74 | TTR (0.68) | CA2CDK2CA1CA9LDHA | |
| SCHEMBL13223071 | 0.72 | CDK2 (0.62) | CA2CDK2CA1CA9LDHA | |
| SCHEMBL28888793 | 0.70 | HTR6 (0.41) | CA2CA1CA9HTTKMT2A | |
| SCHEMBL15851423 | 0.70 | CDK2 (0.70) | CA2CDK2CA1CA9LDHA | |
| SCHEMBL29401806 | 0.70 | CDK2 (1.00) | CA2CDK2CA1CA9LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641742-A4 | COMPOUNDS THAT SELECTIVELY BIND TO MEMBRANES OF APOPTOTIC CELLS | NST NEUROSURVIVAL TECHNOLOGIES (IL) | 2006-11-29 | — | — | EP | disclosed |
| EP-1641742-A2 | COMPOUNDS THAT SELECTIVELY BIND TO MEMBRANES OF APOPTOTIC CELLS | NST Neurosurvival Technologies Ltd. (IL) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004096120-A2 | COMPOUNDS THAT SELECTIVELY BIND TO MEMBRANES OF APOPTOTIC CELLS | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2004-11-11 | — | — | WO | disclosed |