SCHEMBL30525199

SCHEMBL30525199

Cc1ccc(NO)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.56
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
SMN1; SMN2 Q16637 4/20 0.50
ALDH1A1 P00352 2/20 0.50
HTT P42858 1/20 0.50
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
TP53 P04637 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11406554 1.00 RAPGEF4 (0.56) RAPGEF4MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL10882869 0.80 GAA (0.55) RAPGEF4MEN1KMT2AALDH1A1HTT
SCHEMBL30320262 0.79 RAPGEF4 (0.74) RAPGEF4MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL9224379 0.79 RAPGEF4 (0.60) RAPGEF4MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL1334869 0.79 RAPGEF4 (0.74) RAPGEF4MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11406295 0.78 TRPA1 (0.54) MEN1KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL11405183 0.78 MAP2K2 (0.43) RAPGEF4MEN1KMT2AHDAC1HDAC6
SCHEMBL20120093 0.78 KDM4E (0.50) MEN1KMT2AALDH1A1HTTGAA
SCHEMBL1549143 0.77 RAPGEF4 (0.58) RAPGEF4MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL19724286 0.76 SMN1; SMN2 (0.52) RAPGEF4MEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606318-B Preparation method of phosphamide derivative 安阳师范学院 2025-05-27 CN claimed
CN-116574038-B Preparation method of N-aryl sulfonamide derivative 安阳师范学院 2025-04-18 CN claimed
CN-116606318-B Preparation method of phosphamide derivative 安阳师范学院 2025-05-27 CN disclosed
CN-116574038-B Preparation method of N-aryl sulfonamide derivative 安阳师范学院 2025-04-18 CN disclosed
CN-116606318-A Preparation method of phosphamide derivative 安阳师范学院 2023-08-18 CN disclosed
CN-116574038-A Preparation method of N-aryl sulfonamide derivative 安阳师范学院 2023-08-11 CN disclosed