Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413170 | 0.85 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL11415723 | 0.82 | TP53 (0.41) | SMN1; SMN2KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL129333 | 0.82 | TSHR (0.55) | GAASMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL11284034 | 0.81 | NLRP3 (0.43) | SMN1; SMN2KDM4EALDH1A1GLAUSP2 | |
| SCHEMBL6555368 | 0.81 | CHRM1 (0.36) | SMN1; SMN2KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11416672 | 0.80 | CYP3A4 (0.40) | GAASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8673620 | 0.80 | TSHR (0.53) | GAASMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL11421822 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11414429 | 0.79 | KDM4E (0.50) | GAASMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL3716825 | 0.76 | TDP1 (0.36) | KMT2AALDH1A1MAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4214093-A | PROTEOLYTIC ENZYME INHIBITORS | TORII & CO., LTD. (JP) | 1980-07-22 | — | — | US | claimed |
| US-4214093-A | PROTEOLYTIC ENZYME INHIBITORS | TORII & CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |