SCHEMBL129333

SCHEMBL129333

CCOC(=O)c1[c]cccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 1/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
CYP1A2 P05177 2/20 0.46
SMN1; SMN2 Q16637 4/20 0.45
MAPT P10636 4/20 0.44
GAA P10253 2/20 0.44
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8673620 0.98 TSHR (0.53) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL27621725 0.93 TSHR (0.49) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL11284034 0.89 NLRP3 (0.43) TSHRALDH1A1HSD17B10SMN1; SMN2KDM4E
SCHEMBL10434628 0.86 TSHR (0.41) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL130905 0.86 ALDH1A1 (0.58) TSHRALDH1A1HSD17B10SMN1; SMN2MAPT
SCHEMBL3716825 0.83 TDP1 (0.36) TSHRALDH1A1ESR1ESR2KMT2A
SCHEMBL131719 0.83 TSHR (0.60) TSHRALDH1A1HSD17B10CYP1A2SMN1; SMN2
SCHEMBL11413170 0.82 ALDH1A1 (0.46) TSHRALDH1A1MAPTLMNAKDM4E
SCHEMBL11409197 0.82 GAA (0.43) ALDH1A1HSD17B10CYP1A2SMN1; SMN2MAPT
SCHEMBL4630359 0.82 TSHR (0.61) TSHRALDH1A1HSD17B10MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2725 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834532-B2 Photoinitiators IGH RESINS ITALIA S.R.L. (IT) 2023-12-05 US claimed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US claimed
US-11274083-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents SYNGENTA CROP PROTECTION AG (CH) 2022-03-15 US claimed
EP-3728237-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP claimed
EP-3728235-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP claimed
CN-113845427-A Aryl alcohol, aryl ketone, aryl carboxylic acid compound and synthesis method and application thereof 华东师范大学 2021-12-28 CN claimed
EP-3902878-A1 PHOTOINITIATORS IGM Resins Italia S.r.l. (IT) 2021-11-03 EP claimed
CN-113518805-A Photoinitiator 意大利艾坚蒙树脂有限公司 2021-10-19 CN claimed
CN-108947948-B N-aryl naphthofuranone imine compound and synthetic method thereof 湖南大学 2021-07-20 CN claimed
CN-112961093-A Method for reducing C = C double bond of nitroolefin with high selectivity 北京化工大学 2021-06-15 CN claimed
US-4293553-A ANTITHROMBOTIC AGENT Ishikawa, Masayuki (JP) 1981-10-06 US claimed
EP-0003275-B1 AROMATIC DERIVATIVES OF PHOSPHONOFORMIC ACID, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR COMBATING VIRUS INFECTIONS Astra Läkemedel Aktiebolag (SE) 1981-09-02 EP claimed
US-4276295-A VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC Ishikawa, Masayuki (JP) 1981-06-30 US claimed
US-4272529-A ANTIINFLAMMATORY SIMES S.P.A. (IT) 1981-06-09 US claimed
US-4214093-A PROTEOLYTIC ENZYME INHIBITORS TORII & CO., LTD. (JP) 1980-07-22 US claimed
US-4182897-A ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES TORII & CO., LTD. (JP) 1980-01-08 US claimed
US-4009206-A CHOLESTEROL LOWERING AGENTS MURAI HIROMU 1977-02-22 US claimed
US-4005092-A Pyrylium dyes having a fused, rigidized nitrogen-containing ring EASTMAN KODAK COMPANY (US) 1977-01-25 US claimed
US-3956307-A FUNGICIDES SCHERING AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed
US-3932415-A Pyrylium dyes having a fused rigidized nitrogen-containing ring EASTMAN KODAK COMPANY (US) 1976-01-13 US claimed