Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20898646 | 0.74 | ADA (0.36) | ALDH1A1CYP2C19MAPTLMNAGPR84 | |
| SCHEMBL11365598 | 0.73 | PLA2G4A (0.54) | ALDH1A1CYP2C19PLA2G4AMAPTLMNA | |
| SCHEMBL18158115 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2HCAR2KDM4EMEN1 | |
| SCHEMBL27793505 | 0.71 | PLA2G4A (0.52) | ALDH1A1CYP2C19PLA2G4AMAPTLMNA | |
| SCHEMBL22748596 | 0.70 | ALDH1A1 (0.41) | ALDH1A1CYP2C19PLA2G4AMAPTLMNA | |
| SCHEMBL17288867 | 0.69 | PLA2G4A (0.50) | ALDH1A1CYP2C19PLA2G4AMAPTLMNA | |
| SCHEMBL298871 | 0.68 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2KDM4EALOX15TSHR | |
| SCHEMBL27166351 | 0.68 | PLA2G4A (0.41) | PLA2G4AHCAR2FFAR1TDP1 | |
| SCHEMBL18158114 | 0.67 | MME (0.40) | PLA2G4AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20762674 | 0.66 | KMT2A (0.41) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |