Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.41 |
| ▸ | HMGCR | P04035 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793505 | 0.70 | PLA2G4A (0.52) | PLA2G4ATDP1HCAR2 | |
| Bicarbonate SCHEMBL15967903 | 0.65 | PTPN7 (0.75) | PTPN7HMGCRFFAR1FFAR4RECQL | |
| Bicarbonate SCHEMBL15967688 | 0.65 | PTPN7 (0.75) | PTPN7HMGCRFFAR1FFAR4RECQL | |
| Bicarbonate SCHEMBL15967786 | 0.65 | PTPN7 (0.75) | PTPN7HMGCRFFAR1FFAR4RECQL | |
| SCHEMBL167425 | 0.64 | SMN1; SMN2 (0.49) | PLA2G4A | |
| SCHEMBL2383963 | 0.64 | MGLL (0.48) | PTPN7HMGCRFFAR1FFAR4RECQL | |
| SCHEMBL932824 | 0.63 | ALDH1A1 (0.55) | PLA2G4A | |
| SCHEMBL6746703 | 0.63 | NOS1 (0.37) | PTPN7HMGCR | |
| SCHEMBL30143434 | 0.63 | MMP2 (0.72) | PLA2G4AFFAR1FFAR4MMP2MMP12 | |
| SCHEMBL6934491 | 0.63 | MMP2 (0.72) | PLA2G4AFFAR1FFAR4MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |