Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415162 | 0.92 | PAM (0.47) | MCL1PAMLMNAMAPTSMN1; SMN2 | |
| SCHEMBL11421186 | 0.87 | CYP3A4 (0.49) | MCL1CYP3A4LMNAMAPTSMN1; SMN2 | |
| Styrene SCHEMBL28073148 | 0.83 | ALDH1A1 (0.42) | MCL1PAMCYP3A4LMNAMAPT | |
| Methacrylic Acid SCHEMBL6906597 | 0.81 | CYP3A4 (0.46) | MCL1CYP3A4LMNAMAPTSMN1; SMN2 | |
| Methacrylic Acid SCHEMBL437865 | 0.81 | CYP3A4 (0.46) | MCL1CYP3A4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11422112 | 0.81 | GLA (0.47) | MCL1CYP3A4LMNAMAPTSMN1; SMN2 | |
| Methacrylic Acid SCHEMBL863641 | 0.80 | CYP3A4 (0.43) | MCL1CYP3A4LMNAMAPTSMN1; SMN2 | |
| Methacrylic Acid SCHEMBL28068002 | 0.80 | CYP3A4 (0.45) | MCL1CYP3A4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6013130 | 0.80 | CYP3A4 (0.47) | MCL1CYP3A4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8931602 | 0.79 | MAOB (0.39) | MCL1PAMCYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181788-A | Process for the production of thermoplastic molding materials based on vinyl polymers | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-01 | — | — | US | disclosed |