Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415162 | 0.83 | PAM (0.47) | MAOBMCL1MMP1MMP9MMP12 | |
| Acrylonitrile SCHEMBL9665187 | 0.80 | MAOA (0.40) | MAOBLMNAALDH1A1HPGDMAOA | |
| SCHEMBL1034440 | 0.80 | CYP3A4 (0.46) | MAOBMCL1CYP3A4HDAC3HDAC4 | |
| Styrene SCHEMBL9242869 | 0.80 | ALDH1A1 (0.44) | MAOBALDH1A1MAOA | |
| SCHEMBL11409282 | 0.79 | MCL1 (0.43) | MAOBMCL1CYP3A4MMP1MMP9 | |
| Butadiene SCHEMBL29023919 | 0.79 | CYP3A4 (0.43) | MAOBMCL1CYP3A4HDAC3HDAC4 | |
| 1,1-Dichloroethene SCHEMBL9357233 | 0.79 | MAOB (0.50) | MAOBMCL1CYP3A4HDAC3HDAC4 | |
| Butadiene SCHEMBL116599 | 0.78 | MAOB (0.54) | MAOBMCL1CYP3A4MMP1MMP9 | |
| Butadiene SCHEMBL27850381 | 0.78 | MAOB (0.54) | MAOBMCL1CYP3A4MMP1MMP9 | |
| Acrylonitrile SCHEMBL123982 | 0.78 | MAOB (0.54) | MAOBMCL1CYP3A4MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2690989-B2 | — | — | 1997-12-17 | — | — | JP | claimed |
| EP-0375728-A1 | HIGH IMPACT, STYRENIC POLYMER/THERMOPLASTIC POLYMER GRAFTED BLENDS. | ALLIED SIGNAL INC (US) | 1990-07-04 | — | — | EP | claimed |
| WO-1989001962-A1 | HIGH IMPACT, STYRENIC POLYMER/THERMOPLASTIC POLYMER GRAFTED BLENDS | ALLIED-SIGNAL INC. (US) | 1989-03-09 | — | — | WO | claimed |
| US-5461096-A | Nondripping | GENERAL ELECTRIC COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0413972-B1 | Improved thermoplastic compositions which contain polyolefins and polyphenylene ethers, and articles made therefrom | GEN ELECTRIC (US) | 1994-10-12 | — | — | EP | disclosed |
| EP-0550204-A2 | Polyphenylene ether resin compositions | GENERAL ELECTRIC COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5216089-A | Includes modifier comprising of alpha-beta-unsaturated carboxylic acid derivatives | GENERAL ELECTRIC COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5214109-A | Modified polyphenylene ether resins having improved processability and oxidative stability | GENERAL ELECTRIC COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0235266-B1 | TETRAHALOPHTHALATE ESTERS AS FLAME RETARDANTS FOR POLYPHENYLENE ETHER RESINS | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1993-03-03 | — | — | EP | disclosed |
| EP-0502333-A1 | Bromination process | ALBEMARLE CORPORATION (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5055235-A | Heating non-condensed ring polyaromatics in the presence of bromine and a halogenation catalyst | ETHYL CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |
| US-4154775-A | Flame retardant composition of polyphenylene ether, styrene resin and cyclic phosphate | GENERAL ELECTRIC COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4145377-A | MOLDING MATERIALS | GENERAL ELECTRIC COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4129555-A | IMPROVED IMPACT STRENGTH | GENERAL ELECTRIC COMPANY (US) | 1978-12-12 | — | — | US | disclosed |
| US-4127558-A | Compositions of a polyphenylene ether resin and alkenyl aromatic resins modified with EPDM rubber containing propylene | GENERAL ELECTRIC COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4123474-A | STABILIZED THERMOPLASTIC MOLDING MATERIAL | GENERAL ELECTRIC COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4107232-A | HALOGENATED COMPOUND, POLYTETRAFLUOROETHYLENE | GENERAL ELECTRIC (US) | 1978-08-15 | — | — | US | disclosed |
| US-4098846-A | IMPACT STRENGTH | GENERAL ELECTRIC COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4054553-A | MANGANESE COMPLEX CATALYST | GENERAL ELECTRIC COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4002701-A | AND A VINYL AROMATIC RESIN | GENERAL ELECTRIC COMPANY (US) | 1977-01-11 | — | — | US | disclosed |