Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414186 | 0.83 | RAB9A (0.58) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11414189 | 0.83 | RAB9A (0.58) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11410265 | 0.81 | ALDH1A1 (0.55) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11408195 | 0.80 | CHRM5 (0.55) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11404429 | 0.80 | RAB9A (0.58) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL15317952 | 0.80 | KDM4E (0.62) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11408193 | 0.80 | CHRM5 (0.55) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL12694096 | 0.80 | CA2 (0.56) | RAB9AKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL4184857 | 0.80 | CA2 (0.56) | RAB9AKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL4184852 | 0.80 | CA2 (0.56) | RAB9AKDM4EALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |