Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322460 | 0.78 | BCHE (0.73) | BCHELMNATSHRMAPTGAA | |
| SCHEMBL2698571 | 0.78 | BCHE (0.73) | BCHELMNATSHRMAPTGAA | |
| SCHEMBL19139141 | 0.76 | BCHE (0.65) | BCHELMNATSHRMAPTGAA | |
| Biphenyl SCHEMBL5571790 | 0.75 | TSHR (0.54) | LMNATSHRMAPTGAAKDM4E | |
| Biphenyl SCHEMBL3177698 | 0.74 | ALDH1A1 (0.61) | LMNATSHRMAPTGAAKDM4E | |
| SCHEMBL74973 | 0.73 | L3MBTL1 (0.55) | BCHETSHRMAPTGAAALDH1A1 | |
| SCHEMBL31241181 | 0.73 | L3MBTL1 (0.55) | BCHETSHRMAPTGAAALDH1A1 | |
| Biphenyl SCHEMBL9312116 | 0.73 | ALOX15 (0.58) | LMNATSHRMAPTGAAKDM4E | |
| SCHEMBL1966470 | 0.73 | SMN1; SMN2 (0.46) | LMNAMAPTGAAALDH1A1SMN1; SMN2 | |
| Biphenyl SCHEMBL1400697 | 0.72 | ALOX15 (0.62) | LMNATSHRMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181655-A | ANTIDEPRESSANTS | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1980-01-01 | — | — | US | disclosed |