Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TRHR | P34981 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649422 | 0.79 | TRHR (0.43) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10589314 | 0.68 | CREBBP (0.33) | TRHR | |
| Indacrinone SCHEMBL31323234 | 0.68 | HSD17B10 (0.63) | CYP3A4CYP2C9HSD17B10MEN1LMNA | |
| Indacrinone SCHEMBL31323231 | 0.68 | HSD17B10 (0.63) | CYP3A4CYP2C9HSD17B10MEN1LMNA | |
| SCHEMBL27504186 | 0.68 | TRHR (0.41) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL1370995 | 0.68 | TRHR (0.41) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11445107 | 0.65 | TRHR (0.47) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11440014 | 0.65 | TRHR (0.47) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL7775353 | 0.65 | TRHR (0.41) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11231582 | 0.64 | TRHR (0.41) | TRHRHDAC3HDAC11HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036145-A1 | An orally administered drug form comprising a polar bioactive agent and an adjuvant | INTERx RESEARCH CORPORATION (US) | 1981-09-23 | — | — | EP | claimed |