SCHEMBL11409665

SCHEMBL11409665

[O-][N+](=Cc1ccccc1)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 4/20 0.70
ALDH1A1 P00352 9/20 0.50
MAPT P10636 8/20 0.50
ALOX15 P16050 2/20 0.50
TSHR P16473 1/20 0.50
RECQL P46063 1/20 0.50
NPC1 O15118 5/20 0.47
RAB9A P51151 4/20 0.42
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
HSP90AA1 P07900 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
IDO1 P14902 1/20 0.37
TDO2 P48775 1/20 0.37
NFE2L2 Q16236 1/20 0.37
HSD17B10 Q99714 2/20 0.36
FBP1 P09467 1/20 0.36
HPGD P15428 1/20 0.36
EGFR P00533 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11409597 0.86 ALDH1A1 (0.62) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL12355312 0.85 G6PD (0.66) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL2242752 0.85 G6PD (0.66) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL11406437 0.85 G6PD (0.65) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL11411219 0.83 G6PD (0.62) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL2240392 0.82 G6PD (1.00) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL12355268 0.82 G6PD (1.00) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL11406528 0.79 G6PD (0.58) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL264278 0.79 ALDH1A1 (0.73) G6PDALDH1A1MAPTALOX15TSHR
SCHEMBL264277 0.79 ALDH1A1 (0.73) G6PDALDH1A1MAPTALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4224340-A Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds WILLIAM H. RORER, INC. (US) 1980-09-23 US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed