Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.43 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451918 | 0.86 | GPR35 (0.50) | GPR35ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11451916 | 0.86 | GPR35 (0.50) | GPR35ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9100356 | 0.78 | TDP1 (0.43) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9100348 | 0.78 | TDP1 (0.43) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11451379 | 0.77 | GPR35 (0.45) | GPR35ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4386759 | 0.77 | GPR35 (0.46) | GPR35ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1021883 | 0.73 | MEN1 (0.44) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9595282 | 0.73 | KMT2A (0.47) | GPR35ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL30844063 | 0.73 | MEN1 (0.44) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20537519 | 0.73 | HSD17B10 (0.41) | GPR35ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030030-A1 | Derivatives of 2-aminoethanol, processes for their preparation, pharmaceutical compositions containing such compounds and the use the latter | CIBA-GEIGY AG (CH) | 1981-06-10 | — | — | EP | disclosed |