Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844063 | 1.00 | MEN1 (0.44) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL528252 | 0.88 | MAPT (0.39) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL30886752 | 0.88 | MAPT (0.39) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL15017705 | 0.84 | TDP1 (0.60) | MEN1KMT2AMAPTL3MBTL1HSD17B10 | |
| SCHEMBL11743037 | 0.84 | GPR35 (0.49) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL5486010 | 0.83 | HTT (0.44) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL1935386 | 0.81 | KDM4E (0.39) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL10819483 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL11451379 | 0.81 | GPR35 (0.45) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL18555673 | 0.80 | MEN1 (0.41) | MEN1KMT2AKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437955-B | Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase | BASF SE | 2012-10-31 | — | — | CN | disclosed |
| US-8198069-B2 | Method of producing an optically enriched tertiary alcohol from an epoxide using halohydrin dehalogenase | BASF SE (DE) | 2012-06-12 | — | — | US | disclosed |
| EP-1966385-B1 | A process for the production of an optically enriched tertiary alcohol | BASF SE (DE) | 2012-05-02 | — | — | EP | disclosed |
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | BAYER CROPSCIENCE AG (DE) | 2011-10-06 | — | — | US | disclosed |
| US-7993904-B2 | Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase | BASF SE (DE) | 2011-08-09 | — | — | US | disclosed |
| EP-2331512-A1 | ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-1287155-B2 | ENZYMATIC CONVERSION OF EPOXIDES | CODEXIS INC (US) | 2011-01-12 | — | — | EP | disclosed |
| US-7695942-B2 | Enzymatic conversion of epoxides | CODEXIS, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| WO-2010025833-A1 | ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| US-20090275077-A1 | Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides | OXYRANE (UK) LIMITED (GB) | 2009-11-05 | — | — | US | disclosed |
| EP-1158054-A1 | Enzymatic conversion of epoxides | Rijksuniversiteit te Groningen (NL) | 2001-11-28 | — | — | EP | disclosed |
| CN-1282243-A | Pharmaceutical composition containing anilide derivative for antagonizing CCR5 | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
| WO-2000037619-A2 | MUTANT EPOXIDE HYDROLASES | DSM N.V. (NL) | 2000-06-29 | — | — | WO | disclosed |
| EP-1013768-A1 | Mutant epoxide hydrolases | DSM N.V. (NL) | 2000-06-28 | — | — | EP | disclosed |
| US-5763599-A | FOR LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON DNA CHIP | Pfleiderer, Wolfgang (DE) | 1998-06-09 | — | — | US | disclosed |
| CN-1036276-A | Make the method for erect image and negative-appearing image with the static main leaf of photo-hardening | DU PONT (US) | 1989-10-11 | — | — | CN | disclosed |
| US-4859551-A | Process for preparing positive and negative images using photohardenable electrostatic master | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0315121-A2 | Process for preparing positive and negative images using photohardenable electrostatic master | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4269933-A | PHOTOLITHOGRAPHY; POSITIVE AND NEGATIVE IMAGES; POLYMERIZATION OF A UNSATURATED POLYESTER USING A PHOTOSENSITIVE FREE RADICAL SYSTEM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| US-4198242-A | Photopolymerizable composition containing an o-nitroaromatic compound as photoinhibitor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | HAX1, AGPS, PYM1 | MEN1 4149/4885KMT2A 1008/4885KDM4E 721/4885 |
| US-20090275077-A1 | Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides | EPHX2, EPHX1, DERA | MEN1 2316/4885KMT2A 2318/4885KDM4E 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.